ANTIBIOTIC BALYMYCIN, METHOD FOR ITS PRODUCTION AND STRAIN ACTINOMYCETES SPECIES DSM 5908 BEING PRODUCER OF BALYMYCIN

摘要

FIELD: medicine. SUBSTANCE: balymycin having molecular formula C₆₆H₇₃Cl₂N₉O₂₄ is novel glycopeptide antibiotics. It is prepared by cultivation of Actinomycetes species DSM 5908 at 38-32 C within 68-72 h at pH 6-8 at aerobic conditions. Said cultivation is carried out on culture medium which contains sources of carbon, nitrogen, mineral salts and microelements. Desired product is isolated of culture liquid and purified with the help of chromatography. EFFECT: improves quality of desired product. 5 cl, 2 dwg, 3 tbl