Microtetraspora strain for preparation of indolopyrrolocarbazole derivatives

摘要

The resultant compounds of the formula (I) have an excellent antitumor activity.PPA process for preparation of a compound represented by the formula ##STR1## wherein X.sup.1 and X.sup.2 each independently represent hydrogen atom, halogen atom, amino group, mono- or di-lower alkylamino group, hydroxyl group, lower alkoxy group, aralkoxy group, carboxyl group, lower alkoxycarbonyl group, lower alkanoyloxy group or lower alkyl group, andPPR is hydrogen atom, amino group, formylamino group, lower alkanoylamino group, mono- or di-lower alkylamino group, hydroxyl group, lower alkoxy group, aralkoxy group, aralkyl group or lower alkyl group,PP which comprises cultivating a microorganism having an ability to glycosylate a compound represented by the formula ##STR2## wherein X.sup. 1, X.sup.2 and R have the same meanings as defined above, in a nutrient medium containing the compound of the above formula (II), and recovering the formed compound of the formula (I) from the culture medium.