1,4,5,8 tetrakis (hydroxymethyl) naphthalene derivative and its production manner

摘要

PURPOSE: To obtain the subject compound useful as a monomer for polyesters and polyethers, etc., industrially and advantageously by treating 1,4,5,8-tetrakis(hydroxymethyl)naphthalene with an etherifying agent or esterifying agent. ;CONSTITUTION: 1,4,5,8-Tetrakis(hydroxymethyl)naphthalene of formula I is mixed with a mixture of acetic anhydride with pyridine as an esterifying agent and reacted at 60-70°C in a water bath for 20 minutes under stirring. The water bath is removed at a point of time when crystal of the tetraol as the raw material disappeared completely and the reaction mixture is allowed to stand at room temperature. After eight days, the solution is poured to ice-diluted hydrochloric acid, water is added to the solution, precipitating solid is separated and the solid is recrystallized. Otherwise, the tetraol as the raw material is treated with sodium hydride, reacted with methyl iodide as an etherifying agent at 35°C, the reaction mixture is added to water, prepared precipitate is separated and recrystallized to give the objective naphthalene derivative of formula II (OR² is alcohol residue or carboxylic acid residue).;COPYRIGHT: (C)1993,JPO&Japio