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The anti- thrombus, depolymerization sulfuric acid hekisosaminogurukan which possesses tissue element dissolution and anti- inflammation activity, those production manners and it is related the medicine constituent
The anti- thrombus, depolymerization sulfuric acid hekisosaminogurukan which possesses tissue element dissolution and anti- inflammation activity, those production manners and it is related the medicine constituent
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机译:具有组织元素溶解和抗炎活性的抗血栓,解聚硫酸六异氨基古鲁康,其生产方式与药物成分有关
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摘要
Process for the preparation of oligosaccharides by a controlled chemical depolymerization of natural polysaccharides, such as heparins, heparan sulfates, dermatan sulfates, chondroitinsulfates, hyaluronic acid, by a radicalic reaction in an aqueous solution, at a temperature ranging between 20 DEG and 70 DEG C., in the presence of a catalyst selected in the group consisting of Cu++, Fe++, Cr+++, Cr2O7- as well as the resulting oligosaccharides and their related pharmaceutical compositions. The products exhibit high antithrombotic activity, little or no anticoagulant activity, high fibinolytic activity an antiinflammatory activity.
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