Derivatives of amidinofenilalanina antithrombotic and amidino - piridilalanina

摘要

A compound of formula (i): Figure 1 or a pharmaceutically acceptable Salt thereof, or a pharmaceutically acceptable solvate which any entity,In which X is n or CH, and optionally a alquileno c3-c5 monoinsatu erate with an optionally substituted c1-c4 alkyl R1 is H, Methyl or;A c1-c4 alkyl, optionally substituted with a c1-c4 alkoxyl, Oh, nr5r6, conr5r6,A CI cloalquilo C3 C6; aryl; or a alquenilo C3 C6; R2 is H, a c1-c4 alkyl, optionally substituted with a c1-c4 alkoxyl, Oh, nr5r6, conr5r6,A CI cloalquilo C3 C6 or aryl; or conr5r6; R3 and R4 are selected each way independent of h; a c1-c4 alkyl substituted op additionally with a nr5r6; a c1-c4 alkoxyl; Halo; CoNr5r6 and aryl; R5 and R6 are selected each way independent of H and a c1-c4 alkyl; M and N are each independently 1, 2 or 3