PHARMACEUTICAL FORMULATION OF CEFACLOR, DISPERSIBLE TABLETS FROM THEM AND PROCESS FOR PRODUCING THESE TABLETS

摘要

Pharmaceutical formulations of cefaclor, suitable for the direct-compression manufacture of dispersible tablets, containing the antibiotic cefaclor in an amount between 35% and 50% by weight of the total weight of the formulation, along with suitable excipients and coadjuvants selected from disintegrators, diluents, lubricants, antiadherents, sweeteners, fragrances and, optionally, flavorings, opacifiers and colorants. Said formulations are suitable for the manufacture of dispersible tablets which disintegrate in less than three minutes in water at 19 DEG - 21 DEG C, and are suitable for the treatment of infections caused by bacteria strains sensitive to cefaclor.