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BIODEGRADABLE, SUBSTANTIALLY WATER INSOLUBLE, NON-CROSSLINKED POLYMERS HAVING LIPOPHILIC METHYLENE DIESTER MOIETIES PENDANT FROM THE (NON-POLYPEPTIDE) BACKBONE
BIODEGRADABLE, SUBSTANTIALLY WATER INSOLUBLE, NON-CROSSLINKED POLYMERS HAVING LIPOPHILIC METHYLENE DIESTER MOIETIES PENDANT FROM THE (NON-POLYPEPTIDE) BACKBONE
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机译:生物可降解的,基本上不溶于水的,非交联的聚合物,具有(非多肽)主链上的脂族亚甲基二酯部分
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PCT No. PCT/GB93/00469 Sec. 371 Date Jan. 10, 1995 Sec. 102(e) Date Jan. 10, 1995 PCT Filed Mar. 5, 1993 PCT Pub. No. W093/18070 PCT Pub. Date Sep. 16, 1993The invention relates to non-crosslinked non-polypeptide polymers containing biodegradable lipophilic side chains incorporating methylene diester units of the formula -[-CO-O-C(R1R2)-O-CO-]-, where R1 and R2 each represents a hydrogen atom or a carbon-attached monovalent organic group or R1 and R2 together form a carbon-attached divalent organic group. The lipophilic moieties are biodegradatively cleavable to yield a water-soluble polymer.
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