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Process for the preparation of a drug release coating material for prolonged-release acrylate formulations containing (meth) acrylate copolymers
Process for the preparation of a drug release coating material for prolonged-release acrylate formulations containing (meth) acrylate copolymers
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机译:制备用于含有(甲基)丙烯酸酯共聚物的丙烯酸酯缓释制剂的药物释放涂料的方法
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摘要
A coating material for controlling drug release, useful for long acting formulations (e.g. for once-a-day administration), and a long acting granular composition comprising a drug (especially one conventionally difficult to prepar in long acting form) coated with the coating material. This composition may be mixed with other granular drug formulations. The drug-release controlling coating material may comprise, in a specific ratio, specific water-insoluble and low water-permeability polymer and two materials differing from each other in the pH-dependency of their solubility (pH-dependent polymer materials).
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