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NITROGENOUS ESTERIC DERIVATIVE OF THEOPHYLLINE-8-PHENACYLHYDRAZONE AND PREPARATION PROCESS THEREFOR
NITROGENOUS ESTERIC DERIVATIVE OF THEOPHYLLINE-8-PHENACYLHYDRAZONE AND PREPARATION PROCESS THEREFOR
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机译:茶碱8-苯乙酰氮的氮酯衍生物及其制备工艺。
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摘要
The invention relates to N-(2-hydroxyethyl)-p-nitrogenousphenacyl-8-theophyllinehydrazone, as well as to a process for preparing the same. The process consists in treating -chlorophenacyl-8-theopyllinehydrazone with nitrogenous monoethanole amine nitrate in absolute ethylic alcohol medium, in the presence of anhydrous potassium carbonate. The derivative is a solid compound, soluble in organic solvents, hardly soluble in water, ethylic alcohol, acetone, with antihipertensive and coronary-dillating properties.
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