首页> 外国专利> NITROGENOUS ESTERIC DERIVATIVE OF THEOPHYLLINE-8-PHENACYLHYDRAZONE AND PREPARATION PROCESS THEREFOR

NITROGENOUS ESTERIC DERIVATIVE OF THEOPHYLLINE-8-PHENACYLHYDRAZONE AND PREPARATION PROCESS THEREFOR

机译:茶碱8-苯乙酰氮的氮酯衍生物及其制备工艺。

摘要

The invention relates to N-(2-hydroxyethyl)-p-nitrogenousphenacyl-8-theophyllinehydrazone, as well as to a process for preparing the same. The process consists in treating -chlorophenacyl-8-theopyllinehydrazone with nitrogenous monoethanole amine nitrate in absolute ethylic alcohol medium, in the presence of anhydrous potassium carbonate. The derivative is a solid compound, soluble in organic solvents, hardly soluble in water, ethylic alcohol, acetone, with antihipertensive and coronary-dillating properties.
机译:本发明涉及N-(2-羟乙基)-对-氮苯甲酰基-8-茶碱zone及其制备方法。该方法包括在无水碳酸钾存在下,在无水乙醇培养基中,用含氮的单乙醇胺硝酸盐处理-氯苯甲酰基-8- theopyllinehydrazone。该衍生物是一种固体化合物,可溶于有机溶剂,几乎不溶于水,乙醇,丙酮,具有抗高血压和冠心病的特性。

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