method for evaluating in vitro by means of analysis of risk of developing type 2 diabetes by individuals euglicemici.

摘要

it is described a method for the evaluation, for the purpose of diagnosis, prophylaxis, and prevention, of the degree of risk on the part of an individual euglicemico, of developing type ii diabetes.the method includes determining in vitro activity of the enzyme pdh (pyruvate dehydrogenase) in a sample of cells derived from the blood of the individual.in the presence and / or in the absence of stimulation with insulin or with a drug of the class of solfoniluree at defined concentrations by using them as parameters of comparison to the activity of the enzymein these cells of diabetic and non-diabetic subjects.