CHEMI-LUMINISCENT ACRIDINARY DERIVATIVES AND THEIR EMPLOYMENT IN LIGHTENING IMMUNOANALYSIS.

摘要

CHEMI-LUMINISCENT ACRIDINE DERIVATIVE OF FORMULA (I) IN WHICH R1 IS HYDROGEN, ALKYL, ALKYNYL, OR A REST OF ALKYNYL WITH 1 TO 10 ATOMS OF, A BENCIL OR ARYL GROUP; R2 AND R3 ARE HYDROGEN, AN ALKYL GROUP WITH 1 TO 4 CARBON ATOMS, AN AMINO GROUP SUBSTITUTED OR NOT, A CARBOXI GROUP, C1-C4ALCOXICIAN-, NITRO-, OR WITH HALOGENES, R4 A REST IN WHICH A SULPHONAMID GROUP IS COMBINED DIRECTLY WITH A CARBONYL GROUP OR A REST THIOALKYL OR THIOARYL OF FORMULA -SX-R5, IN WHICH X IS A BRANCHED ALIPHATIC OR AROMATIC GROUP, OR WHICH MAY ALSO HAVE A HETERO-ATOMS AND R5 ONE GROUP WILL HAVE A REACT SELECTIVE WITH AMINO-, CARBOXI-, TIOL- OR OTHER FUNCTIONAL GROUPS IN SUBSTANCES OF BIOLOGICAL INTEREST, AND A- IT IS AN ANION THAT HURTS THE CHEMIOLUMINESCENCE AS WELL AS ITS USE IN LUMINISCENT ENZYME TESTS.