NEW ANALOGS OF TIMOPENTINE THAT HAVE ONE OR MORE RETROINVERTED LINKS, A METHOD FOR SYNTHESIZING THEM, AND THEIR USE FOR THE PREPARATION OF PHARMACEUTICAL PRODUCTS.

摘要

NEW TIMOPENTINE ANALOGS (TP5) ARE DISCOVERED WHICH CONTAINS ONE OR MORE INVERTED RETRO LINKS IN THEIR REQUESTED CHAIN. THE NEW COMPOUNDS HAVE ONE OF THE FOLLOWING GENERAL FORMS (I), (II) OR (III) WHERE R IS HYDROGEN OR A RADICAL ACIL, AND R1 IS A GROUP OF FORMULA -OR2 WHERE R2 IS AN ATOM OF HYDROGEN OR A RADICAL HYDROCARBON, AND THE CORRESPONDING SALTS OF PHARMACEUTICALLY ACCEPTABLE ACIDIC OR BASIC ADDITION. SUCH NEW COMPOUNDS HAVE IMMUNO-STIMULATING ACTIVITY.