STABLE PHARMACEUTICAL COMPOSITION OF 3- (HYDROXIMETIL) -5,5-DIPHENYL HYDANTOINE PHOSPHATE ESTER.

摘要

A STABLE PHARMACEUTICAL COMPOSITION OF ESTER 3- (HYDROXYMETHYL) -5, 5-DIPHENYLHIDANTONINE DISODIC PHOSPHATE, PRO MEDICATION OF 5, 5-DIPHENYL HYDANTONINE (PHENITOIN), A COMMONLY USED TREATMENT AND TREATMENT, IS DESCRIBED CONVULSIVE STATES. IT IS KNOWN THAT THE DEGRADATION OF PENTINA PRODROGUE CAN BE CONTROLLED BY CONTROLLING THE PH OF THE COMPOSITION. CONTROLLING THE PH BETWEEN 8.3 AND 9.4 OF A RESULT OF A PRODUCTION OF DIPHENYLGLYCINAMIDE AS THE PRIMARY DEGRADANT AND MINIMIZATION OF DEGRADATION TO FENTONIA. IF THE PH IS MAINTAINED IN A LOWER OR HIGHER VALUE, THEN THE PATTERN OF DEGRADATION CHANGES, WITH A FAILURE OF THE PRODUCT EARLIER THAN EXPECTED.