Stabilization of blood platelets against low temperature activation

摘要

Spontaneous activation of platelets at the low temperatures normally used for blood storage is reduced or eliminated by treating the platelets with thermal hysteresis proteins. Preferred thermal hysteresis proteins are antifreeze proteins and antifreeze glycoproteins from polar fish species, and chromatographic fractions Nos. 2-6 of antifreeze glycoproteins have been found to be particularly effective.