首页> 外国专利> Flavin adenine dinucleotide analogues, their pharmaceutical compositions, and their activity as monoamine oxidase inhibitors

Flavin adenine dinucleotide analogues, their pharmaceutical compositions, and their activity as monoamine oxidase inhibitors

机译:黄素腺嘌呤二核苷酸类似物,其药物组成及其作为单胺氧化酶抑制剂的活性

摘要

The present invention provides an inhibitor of monoamine oxidase comprising a modified synthetic flavin adenine dinucleotide compound. Also provided is a method of inhibiting monoamine oxidase enzymatic activity in a cell, comprising the step of contacting said cell with a pharmacologically effective dose of a modified synthetic flavin adenine dinucleotide compound. Further provided is a method of treating a brain pathophysiological state in an individual, comprising administering a therapeutically effective dose of a modified synthetic flavin adenine dinucleotide compound to said individual.
机译:本发明提供了单胺氧化酶的抑制剂,其包含修饰的合成黄素腺嘌呤二核苷酸化合物。还提供了一种抑制细胞中单胺氧化酶酶活性的方法,该方法包括使所述细胞与药理学有效剂量的修饰的合成黄素腺嘌呤二核苷酸化合物接触的步骤。进一步提供了一种治疗个体的脑病理生理状态的方法,其包括向所述个体施用治疗有效剂量的修饰的合成黄素腺嘌呤二核苷酸化合物。

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