BORONIC ACID AND ESTER INHIBITORS OF THROMBIN BORONIC ACID AND ESTER INHIBITORS OF THROMBIN

摘要

Novel boronic acid and ester and carboxyl-modified amino acid compounds of formula (I): R?1-Z-CHR1¿-A, which are inhibitors of trypsin-like enzymes, are disclosed, where R?1, Z, R2¿ and A are defined within.