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DNA ENCODING INWARD RECTIFIER, G-PROTEIN ACTIVATED, MAMMALIAN, POTASSIUM KGA CHANNEL AND USES THEREOF

机译:DNA编码内向整流子,活化的G蛋白,哺乳动物,钾钾通道及其用途

摘要

Nucleic acids encoding mammalian "KGA" potassium channels are provided. Vectors and transformed host cells are also provided. The KGA channels exhibit inward rectification and are activated by a G-protein. The products of the invention are useful in screening assays to identify modulators of the KGA channel and in methods for identifying or preparing nucleic acids encoding the KGA channel or related potassium channels.
机译:提供了编码哺乳动物“ KGA”钾通道的核酸。还提供了载体和转化的宿主细胞。 KGA通道显示向内整流,并被G蛋白激活。本发明的产物可用于筛选测定以鉴定KGA通道的调节剂,以及用于鉴定或制备编码KGA通道或相关钾通道的核酸的方法。

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