首页> 外国专利> USE OF ANTIBODIES AGAINST $g(b)-2 MICROGLOBULIN-FREE, CLASS I HLA MOLECULES TO PROVIDE HIV DIAGNOSTIC TESTS AS WELL AS COMPOSITIONS HAVING A PROTECTIVE ACTION AGAINST HIV INFECTIONS

USE OF ANTIBODIES AGAINST $g(b)-2 MICROGLOBULIN-FREE, CLASS I HLA MOLECULES TO PROVIDE HIV DIAGNOSTIC TESTS AS WELL AS COMPOSITIONS HAVING A PROTECTIVE ACTION AGAINST HIV INFECTIONS

机译:使用不含$ g(b)-2的微球蛋白I类HLA分子的抗体提供HIV诊断测试以及对HIV感染具有保护作用的成分

摘要

use of an antibody able to recognize both epitopi gp160 protein of hiv and the heavy chain of hla class 1 free from microglobulin. - 2(hla fhc) for the production of a diagnostic test for the presentation of hiv infection in a analito negative for the presence of hiv specific antibodies.said paper characterized by the following steps: - incubate said analito with a sample consisting of hla molecules fhc.immobilized on a solid support.under such conditions as to allow the formation of a complex analito - hla fhc; washing with a buffer under conditions that do not dissocianti for said compound; incubating said complex with said antibodyunder such conditions as to allow the formation of a complex analito fhc hla antibody; reveal said complex analito - fhc hla antibody.
机译:能够识别HIV抗原决定簇gp160蛋白和不含微球蛋白的hla 1类重链的抗体的应用。 -2(hla fhc)用于产生诊断试验,用于在存在hiv特异性抗体的阴性动物中呈现hiv感染。该论文的特征在于以下步骤:-将所述analito与由hla分子组成的样品孵育fhc。固定在固体支持物上,条件是允许形成复杂的analito-hla fhc;在不离解所述化合物的条件下用缓冲液洗涤;在允许形成复合物analito fhc hla抗体的条件下,将所述复合物与所述抗体一起温育;揭示了所述复杂的analito-fhc hla抗体。

著录项

  • 公开/公告号EP0717847A1

    专利类型

  • 公开/公告日1996-06-26

    原文格式PDF

  • 申请/专利权人 FONDAZIONE CENTRO SAN RAFFAELE DEL MONTE TABOR;

    申请/专利号EP19940927036

  • 发明设计人 BERETTA ALBERTO;

    申请日1994-09-06

  • 分类号G01N33/569;G01N33/543;G01N33/554;

  • 国家 EP

  • 入库时间 2022-08-22 03:46:45

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