Aminomethylindane,-benzofuran and-benzothiophene (AMINOMETHYLINDANS,-BENZOFURANES AND-BENZOTHIOPHENES)

摘要

General formula (I):;Wherein one of X and Y is CH₂And the other is CH₂, O or S; R^OneAn aliphatic hydrocarbon group, an arylalkyl group, an acyl group, a sulfonyl group, a carbonate group, or R¹¹R¹²NCO-(wherein R¹¹And R¹²Is selected from hydrogen and hydrocarbon groups; R²Is hydrogen or a hydrocarbon group; R³To R⁵Is selected from hydrogen, halogen, alkyl, alkoxy, alkylthio, hydroxy, alkylsulfonyl, cyano, trifluoromethyl, cycloalkyl, cycloalkylalkyl,⁶And R⁷Are each hydrogen or lower alkyl or combine together to form a carbon ring ring; R⁸And R⁹Is independently hydrogen, a hydrocarbon group or;(Wherein R¹³Is hydrogen or a hydrocarbon group, W is O or S, and r is 2 to 6,_1AHas efficacy in receptors and is useful in the treatment of psychoses, anxiety disorders, depression, impulse control disorders, alcoholism, aggression, anemia, side effects induced by conventional antipsychotic medications, or cardiovascular disorders.