Piperidine derivatives as calcium channel antagonists (Piperidine Derivatives as Calcium Channel Antagonists)

摘要

The present invention relates to a calcium antagonist, for example a compound of formula (I) or a salt thereof, useful for the treatment of conditions associated with the accumulation of calcium in brain cells.;Wherein R^OneC_1-6Alkyl, halogen or phenyl, R²Is a hydrogen atom, C_1-6Alkyl, halogen or phenyl and R³Is a hydroxyl or a group which can be converted in vivo to a hydroxyl group, R⁴C_1-6Alkyl, p is 0, 1 or 2, X is-CH₂-,-C O, O or S, n is an integer of 4 to 10, and m is an integer of 3 to 8.