Quinuclidine and azabicyclo 2. RTI ID = 0.0 2.1 heptanepyrazinyl ether

摘要

The compound of formula (I) or a pharmaceutically acceptable salt thereof is a pivotal active muscarinic agonist.;Wherein Y is oxygen or sulfur; A is oxygen, sulfur or-NR₂(Wherein R₂Is hydrogen or alkyl of 1 to 6 carbon atoms; R is selected from the group consisting of ethyl, propyl, isopropyl, isobutyl, 2,2,2-trifluoroethyl, 3,3,3-trifluoropropyl, 1-trifluoromethyl-2,2,2-Ethyl, 2-trifluoromethyl-3,3,3-trifluoropropyl, cyclopropyl, cyclopropylmethyl, cyclopropylethyl, cyclobutyl, cyclobutylmethyl, cyclopentyl, cyclopentylmethyl, cyclohexyl, cyclohexyl Methyl, thienyl, thienylmethyl, phenyl or benzyl; and n is an integer of 1 or 2.