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TYPE S_3N_2 CHELATORS FOR RADIOACTIVE ISOTOPES, THEIR METAL COMPLEXES AND THEIR DIAGNOSTIC AND THERAPEUTICAL USE for Radioactive Isotopes
TYPE S_3N_2 CHELATORS FOR RADIOACTIVE ISOTOPES, THEIR METAL COMPLEXES AND THEIR DIAGNOSTIC AND THERAPEUTICAL USE for Radioactive Isotopes
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机译:放射性同位素的S_3N_2型隔离物,其金属络合物以及放射性同位素的诊断和治疗用途
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摘要
The present invention relates to novel bifunctional chelating agents having intermittent chalcogen atoms, medicaments containing these compounds, their use in radiation diagnostics and radiation therapy, and methods of making these compounds. The compound according to the present invention is a compound of the following general group (I). M-L (I) wherein M is a radionuclide of Rc or Re and L is a ligand of formula (II). Surprisingly, it has been found that novel bifunctional chelating agents with intermittent chalcogen runners and their coupling products with their specially accumulating compounds are very suitable for the manufacture of radiopharmaceuticals for diagnostic and therapeutic purposes.
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