7-ACETYL-6-METHOXY-3-METHYL-1-PHENYL-1H-1,2-DIAZAPHENALENE SHOWING HYPOTENSIVE ACTIVITY

摘要

FIELD: organic chemistry. SUBSTANCE: product: 7-acetyl-6-methoxy-3-methyl-1-phenyl-1H-1,2-diazaphenalene of the formula (I) , empirical formula is C₂₁H₁₈N₂O₂, yield is 70% m. p. is 118 C. Reagent 1: 6-methoxy-3-methyl-1-phenyl-1H-1,2-diazaphenalene. Reagent 2: Wilsmeier reagent POCl + CH-C(O)N(CH). Reaction conditions: heating at 85-90 C for 30 min. Synthesized compound is used in pharmaceutical chemistry. EFFECT: improved method of synthesis.