DELAYED DRUG DELIVERY THROUGH TOPICAL APPLICATION OF BIOADHESIVE LIPOSOMES.

摘要

Drug-encapsulating liposomes have been successfully modified through the covalent binding of recognizing substances without significant interference with the rate constant of drug efflux from the liposomes. Through data processing according to two mechanisms, the acceptability of the bioadhesive liposomes as sustained release drug delivery systems for topical or local administration is shown.