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Separation of enantiomers of non-steroidal anti-inflammatory drugs and chiral selector therefor

机译:非甾体类抗炎药对映体的分离及其手性选择剂

摘要

The invention relates to a chiral selector useful in separating underivatized enantiomers of nonsterodial anti-inflammatory agents, particularly naproxen and other arylacetic acid compounds, and relates to a process for achieving such separation utilizing the chiral selector, which is also useful in achieving the enantiomeric separation of amines, alcohol derivatives, epoxides and sulfoxides. The invention is also directed to an apparatus which comprises the chiral selectors.
机译:本发明涉及用于分离非立体抗炎剂,特别是萘普生和其他芳酸化合物的未衍生化对映异构体的手性选择剂,并涉及利用手性选择剂实现这种分离的方法,该方法也可用于实现对映体分离胺,醇衍生物,环氧化物和亚砜。本发明还涉及一种包括手性选择剂的设备。

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