Naphthyl compounds, intermediates, processes, compositions, and method of inhibiting aortal smooth muscle cell proliferation

摘要

The present invention provides a compound of formula I ##STR1## wherein R.sup.1 is --H, --OH, --O(C.sub.1 -C.sub.4 alkyl), -- OCOC.sub.6 H. sub.5, --OCO(C.sub.1 -C.sub.6 alkyl), or --OSO.sub.2 (C.sub. 4 -C.sub.6 alkyl);PPR.sup.2 is --H, --OH, --O(C.sub.1 -C. sub.4 alkyl) , --OCOC.sub.6 H.sub.5, --OCO(C.sub.1 -C.sub.6 alkyl) or -- OSO.sub.2 (C. sub.4 -C.sub.6 alkyl);PPn is 2 or 3; and PP R.sup.3 is 1-piperidinyl, 1-pyrrolidinyl, methyl-1- pyrrolidinyl, dimethyl- 1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, or 1- hexamethyleneimino; or a pharmaceutically acceptable salt thereof, for inhibiting aortal smooth muscle cell proliferation.