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Method and reagents for binding chemical analytes to a substrate surface, and related analytical devices and diagnostic techniques
Method and reagents for binding chemical analytes to a substrate surface, and related analytical devices and diagnostic techniques
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机译:用于将化学分析物结合到基材表面的方法和试剂,以及相关的分析装置和诊断技术
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摘要
A method is provided for detecting an analyte of interest in a sample. The method involves binding the analyte to the surface of a substrate through a biotin-biotin binding protein interaction, contacting the surface-bound analyte with a quantitatively detectable analyte- binding moiety that binds thereto, measuring the quantity of detectable moiety bound to the substrate surface and deriving therefrom the quantity of analyte in solution. A preferred use for the present method is in conjunction with a piezoelectric surface transverse wave device. Novel reagents useful for carrying out the inventive method are provided as well.
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