首页>
外国专利>
Methods of detecting disorders of the central nervous system by detecting autoantibodies which specifically bind ionotropic glutamate receptors
Methods of detecting disorders of the central nervous system by detecting autoantibodies which specifically bind ionotropic glutamate receptors
展开▼
机译:通过检测特异性结合离子型谷氨酸受体的自身抗体来检测中枢神经系统疾病的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method of screening a subject for a central nervous system disorder caused by autoimmune disease (e.g., an inflammatory seizure disorder) comprises a sample from the subject and then detecting the presence or absence of anti-glutamate receptor autoantibodies (e.g., anti- GluR3 glutamate receptor autoantibodies) in the biological sample. The presence of such autoantibodies indicates the subject is afflicted with a central nervous system disorder caused by autoimmune disease. Methods of treating such disease by reducing the number of autoantibodies available to bind to glutamate receptors in the subject are also disclosed.
展开▼