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9-deazaadenosine and its 5'--D-glycopyranoside isolated from the cyanobacterium anabaena affinis strain VS-1
9-deazaadenosine and its 5'--D-glycopyranoside isolated from the cyanobacterium anabaena affinis strain VS-1
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机译:从花青细菌亲和力菌株VS-1中分离得到9-脱氮杂腺苷及其5'-D-吡喃葡萄糖苷
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摘要
The present invention is based upon the discovery that a MeOH extract of Anabaena affinis strain VS-1 showed strong cytotoxicity to L1210 murine leukemia cells, and from that extract was isolated the compounds having the following structures, Compounds 1 and 2. These two compounds are believed to be responsible for the cytotoxicity of the marine organism. This is the first report of the isolation and characterization of pyrrolo[3,2-d] pyrimidine derivatives as biosynthetic products. ##STR1##
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