首页> 外国专利> tumor targeting used consists of radioactive nuclides immune response agents and chelated the L- enantiomeric oligonucleotide complex

tumor targeting used consists of radioactive nuclides immune response agents and chelated the L- enantiomeric oligonucleotide complex

机译:所用的肿瘤靶向物由放射性核素免疫反应剂和螯合的L-对映体寡核苷酸复合物组成

摘要

(57) A non-radioactive targeting immunoreagents, immunoreactive group, non-self associating L- enantiomeric oligonucleotide sequence of one or more, and [Abstract] The present invention, those containing the linking group of 1 or more, can be, as well as a radioactive targeting immune reagents, is complementary in sequence to a fragment of one or more of the non-self-association of L- enantiomeric oligonucleotide sequences to hybridize with the fragment L- enantiomeric oligonucleotide sequence , which is directed chelating agents, one or more linking groups of 1 or more, and containing one radionuclide or more. The present invention, I is directed to pharmaceutical compositions comprising a pharmaceutically acceptable carrier and the immunity one or more reagents. The invention is further directed to a method for the imaging and treatment of disease sites in a patient.
机译:(57)一种非放射性靶向免疫试剂,免疫反应基团,一个或多个非自缔合的L-对映体寡核苷酸序列,以及[摘要]本发明,包含一个或多个连接基团的那些,也可以是作为一种放射性靶向免疫试剂,它与L-对映体寡核苷酸序列的一个或多个非自缔合的片段在序列上互补,以与L-对映体寡核苷酸序列的片段杂交,后者是定向螯合剂,一种或多种1个或多个且包含一个或多个放射性核素的更多连接基团。本发明涉及包含药学上可接受的载体和免疫力的一种或多种试剂的药物组合物。本发明还涉及一种用于对患者的疾病部位进行成像和治疗的方法。

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