首页> 外国专利> COMPOSITION WITH ACTION ON BACTERIA, FILAMENTOUS FUNGUS AND VIRUS AND BASED ON ALPHA-HYDROXYALKANIC ACID AND SQUALENE

COMPOSITION WITH ACTION ON BACTERIA, FILAMENTOUS FUNGUS AND VIRUS AND BASED ON ALPHA-HYDROXYALKANIC ACID AND SQUALENE

机译:基于α-羟基碱性酸和方酸的对细菌,丝状真菌和病毒有作用的组合物

摘要

PROBLEM TO BE SOLVED: To prepare a composition, effective is antibacterial, antimold or antiviral uses, especially against Gram-positive bacteria and excellent in safety by combining a specific -hydroxycarboxylic acid with squalene. SOLUTION: This composition contains a combination of an - hydroxycarboxylic acid of formula I (R' and R" are each H, an alkyl or phenyl or R' and R" together form a cycloalkyl), its physiologically permissible salt, ethyl ester or methyl ester with squalene. For example, compounds of formula II [(n) is 7-31] and formula III are cited as the compound of formula I. The content of the -hydroxycarboxylic acid is about 20-30wt.% based on the whole composition. The combination of the compound of formula I with the squalene is blended in an amount of preferably about 0.005-50.0wt.%, especially preferably about 0.01-20.0wt.% based on the whole composition. The composition is capable of suppressing especially the proliferation of Pityrosporum ovale and can be used for preventing the formation of dandruff and treating common acne, etc.
机译:解决的问题:为了制备组合物,有效的是抗细菌,抗霉菌或抗病毒的用途,特别是针对革兰氏阳性细菌,并且通过将特定的羟基羧酸与角鲨烯混合使用,具有出色的安全性。溶液:此组合物包含式I的羟基羧酸(R'和R“各自为H,烷基或苯基或R'和R”共同形成环烷基),其生理上允许的盐,乙酯或甲基与角鲨烯的酯。例如,式II的化合物[(n)为7-31],式III的化合物被引用为式I的化合物。基于整个组合物,-羟基羧酸的含量为约20-30wt。%。式I化合物与鲨烯的组合以基于整个组合物的优选约0.005-50.0wt。%,特别优选约0.01-20.0wt。%的量共混。该组合物尤其能够抑制卵圆形糠ity孢子菌的增殖,并且可以用于防止头皮屑的形成和治疗普通痤疮等。

著录项

  • 公开/公告号JPH09169629A

    专利类型

  • 公开/公告日1997-06-30

    原文格式PDF

  • 申请/专利权人 BEIERSDORF AG;

    申请/专利号JP19960324843

  • 申请日1996-11-21

  • 分类号A61K7/48;A61K7/00;A61K7/06;A61K7/075;A61K7/08;A61K7/32;A61K31/01;A61K31/19;A61K31/20;A61K31/22;A61K31/23;

  • 国家 JP

  • 入库时间 2022-08-22 03:33:27

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