首页> 外国专利> Procedure for the preparation of (2R, 3S) - 3 - (benzoylamino - 2 - hydroxy - 3 - Phenylpropionate 4.10 - benzoyloxy diacetoxi - 2 or - beta - 5, 20 - epoxy - 17 beta - dihydroxy - 9-oxo - Tax - 11 - 13 - or - ilo Trihydrate and Trihydrate thus obtained

Procedure for the preparation of (2R, 3S) - 3 - (benzoylamino - 2 - hydroxy - 3 - Phenylpropionate 4.10 - benzoyloxy diacetoxi - 2 or - beta - 5, 20 - epoxy - 17 beta - dihydroxy - 9-oxo - Tax - 11 - 13 - or - ilo Trihydrate and Trihydrate thus obtained

机译:制备(2R,3S)-3-(苯甲酰氨基-2-羟基-3-苯丙酸酯4.10-苯甲酰氧基二醋-2或-β-5,20-环氧-17β-二羟基-9-氧-税收-由此获得的11-13-或-ilo三水合物和三水合物

摘要

This is a procedure for the preparation of (2R, 3S) - 3 - (benzoylamino - 2 - hydroxy - 3 - Phenylpropionate 4.10 - - - - diacetoxi 2u00d3 benzoyloxy 5u00df, 20 epoxy - 1.7 beta dihydroxy - 9-oxo - Tax - 11 - - - i 13u00d3 Trihydrate,By crystallization from a mixture of water and ethanol (alcohol C1 - C3) and reduced Lubricating Vacuum drying of the product.The Product obtained was eventually preserved atmosphere relative humidity lower than 20%. It also justifies the trihidratoobtenido.
机译:这是制备(2R,3S)-3-(苯甲酰氨基-2-羟基-3-苯丙酸酯4.10----二醋甲酮2 u00d3苯甲酰氧基5 u00df,20环氧-1.7β二羟基-9-氧代的程序-税-11---i 13 u00d3三水合物,通过从水和乙醇(酒精C1-C3)的混合物中结晶并降低产品的润滑真空干燥度,最终获得的产品在大气中的相对湿度低于20%这也证明了Trihidratoobtenido是有道理的。

著录项

  • 公开/公告号AR001072A1

    专利类型

  • 公开/公告日1997-09-24

    原文格式PDF

  • 申请/专利权人 RHONE-POULENC RORER S.A.;

    申请/专利号AR19960335171

  • 发明设计人

    申请日1996-01-24

  • 分类号C07D305/14;A61K31/335;

  • 国家 AR

  • 入库时间 2022-08-22 03:27:50

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