HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES, PHARMACEUTICAL PREPARATIONS AND DEPOT PHARMACEUTICAL PREPARATIONS IN WHICH SAID COMPOUNDS ARE COMPRISED AND THE USE OF THE COMPOUNDS AS ANTIPSYCHOTICS AND ANALGESICS

摘要

Heteroarylpiperidines, pyrrolidines, and piperazines of the formula wherein X is -O-, -S-, -NH-, or -N(R 2 )- R 2 is selected from the group consisting of lower alkyl, aryl lower alkyl, aryl, cycloalkyl, aroyl, alkanoyl, alkoxycarbonyl and phenylsulfonyl groups; p is 1 or 2 Y is hydrogen, lower alkyl, hydroxy, chlorine, fluorine, bromine, iodine, lower alkoxy, trifluoromethyl, nitro, or amino; Q 1 is selected from the group consisting of: and where Z is are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.