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It includes the pure reactive compound of particle i.e. insoluble or be only very slightly soluble in water, pharmaceutical carrier itself that method, which prepares the pharmaceutical composition of carrier,
It includes the pure reactive compound of particle i.e. insoluble or be only very slightly soluble in water, pharmaceutical carrier itself that method, which prepares the pharmaceutical composition of carrier,
The preparation method for providing the pharmaceutical composition of carrier includes the insoluble or moderately soluble of the pure reactive compound progress of particle in water or the mixture of at least two compound of particle shows such activity, and wherein active component is solid at room temperature. The manufacture craft is that the active material of the mixture of suspension or active material are homogenized gap by interior piston homogenizer and have average diameter to form particle, by photon correlation spectroscopy at 10 nanometers to 1,000 nanometer, so that group sum of the ratio of particle greater than 5 microns is less than 0.1 (number distribution is measured with Coulter-counter). The pharmaceutical composition for further disclosing carrier includes particle (pure 4- [N- 2-hyroxy-2-methylpropyl ethanolamine] -2), cis- two (7-bis-, 6-dimethylmorpholin-4-yl -6-phenylpteridine), carbamazepine, pantocaine or prednisolone have specified average diameter and particle ratio.
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