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Cationic complexes with technetium-99m, the complexes for use as cardiac imaging agents and ligands useful in such complexes

机译:tech 99m阳离子复合物,用作心脏显像剂的复合物以及可用于此类复合物的配体

摘要

The invention concerns cationic complexes of Technetium-99m with bidentate ligands (L), including complexes having the formulae [Tc(NO) X L2]+ and [Tc L3]+, which are of interest as heart imaging agents. The ligands are characterized by having the formula Y2QZQY2, where each Q is phosphorus or arsenic, Z is a 2 or 3 carbon atom linking group, and at least one of the groups Y and Z includes at least one -COC- ether group.
机译:本发明涉及Technetium-99m与二齿配体(L)的阳离子配合物,包括具有式[Tc(NO)X L2] +和[Tc L3] +的配合物,它们是心脏成像剂。所述配体的特征在于具有式Y 2 QZQY 2,其中每个Q是磷或砷,Z是2或3个碳原子连接基团,并且基团Y和Z中的至少一个包括至少一个-COC-醚基。

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