17beta-aryl and 17beta-heterocyclyl-5beta, 14beta-androstane derivatives having an effect on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing them

摘要

17-Aryl and 17-heterocyclyl-5 beta ,14 beta -androstane derivatives of general formula (I): CHEM wherein: the symbol means that the substituents in position 17 can have an alpha or beta configuration; the symbol --- represents a single or a double bond; Y, R and R1 have the meanings given in the description; a process for producing same, pharmaceutical compositions containing same as active ingredient, and their use in the preparation of a pharmaceutical agent for the treatment of cardiovascular disorders such as heart failure and hypertension are disclosed.