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Methods of using decomposition catalysts for peroxynitrite, pharmaceutical compositions for peroxynitrite, pharmaceutical compositions for the same
Methods of using decomposition catalysts for peroxynitrite, pharmaceutical compositions for peroxynitrite, pharmaceutical compositions for the same
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机译:过氧亚硝酸盐的分解催化剂的使用方法,过氧亚硝酸盐的药物组合物,用于该药物的药物组合物
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摘要
The present invention provides a method for the treatment of diseases by the decomposition of peroxynitrite, preferably decomposition to benign products, comprising the use of a complex which is a selected ligand structure providing a complexed metal such as Mn, Fe, Ni and V transition metals. The method of use, as well as novel pharmaceutical compositions therefor, are for the treatment of diseases advantageously affected by decomposition of peroxynitrite at a rate over the natural background rate of decay of peroxynitrite in humans suffering from the disease which comprises administration of an amount of a complex, in dosage unit form, which is effective for such acceleration of the decomposition of peroxynitrite.
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