THE COMBINATION OF GROWTH HORMONE AND INSULIN-LIKE GROWTH FACTOR-I ENHANCES GROWTH

摘要

PCT No. PCT/US93/10259 Sec. 371 Date Nov. 19, 1993 Sec. 102(e) Date Nov. 19, 1993 PCT Filed Oct. 26, 1993 PCT Pub. No. WO91/18621 PCT Pub. Date Dec. 12, 1991A method is disclosed for treating obese mammals or preventing obesity from occurring in mammals. This method involves administering to the mammal an effective amount of growth hormone in combination with an effective amount of IGF-I. Preferably, the growth hormone is given so as to have a maintained, continual therapeutically effective presence in the blood, such as by continuous infusion or frequent injections, or by use of a long-acting formulation.