AMINOGUANIDINE CARBOXYLATES FOR THE TREATMENT OF NON-INSULIN-DEPENDENT DIABETES MELLITUS.

摘要

The present invention provides novel compounds of the formulae (I): AG-(CH2)n-CO2R1 and (II) or pharmacologically acceptable salts thereof, wherein AG is: a) N-aminoguanidine, b) N,N'-diaminoguanidine, or c) N,N',N"-triaminoguanidine; and n, R1 and R2 have the meanings given in the description as well as a new use for the compounds of formula (III) wherein R3 has the meanings given in the description for the treatment of non-insulin dependent diabetes mellitus (NIDDM).