NAPHTHYRIDINE DERIVATIVES; PREPARATIVE PROCESS AND ANTI-TUMOUR MEDICAMENTS

摘要

This invention relates to pyridone-carboxylic acid derivatives of the following formula or salts thereof: CHEM wherein R1 is a hydrogen atom, a halogen atom, etc., R2 is a carboxyl group etc., R3 is a hydrogen atom etc., A is a nitrogen atom or CH, m is 1 or 2, and Y is an eliminable group or a group having the following formula: CHEM wherein R4 is a hydrogen atom or a lower alkyl group, Z is a hydrogen atom, a lower alkyl group, etc., R5 is a hydrogen atom, a lower alkyl group, etc., n is 0 or 1, and p is 1, 2, 3 or 4 and to processes for the preparation of these compounds, and further to anti-tumor agents which contain the above compounds as effective ingredients.