Process for preparing heterocyclic carbenes by reacting azolium salts with a deprotonation reagent in pure liquid ammonia or in pure organic amine and organic polar aprotic solvent

摘要

PCT No. PCT/EP97/01296 Sec. 371 Date Nov. 2, 1998 Sec. 102(e) Date Nov. 2, 1998 PCT Filed Mar. 14, 1997 PCT Pub. No. WO97/34875 PCT Pub. Date Sep. 25, 1997A process for preparing heterocyclic carbenes of the in which R1, R2, R3 and R4 are individually saturated or unsaturated, straight chain, branched or cyclic, unsubstituted or substituted C1-C10 alkyl, C2-C5 alkylidene, C2-C5 alkylidine, C7-C19 aralkyl or C6-C14 alkyl groups, R3 and R4 can also stand for hydrogen or form jointly anellated, substituted or unsubstituted groups with between 3 and 7 carbon atoms and X stands for carbon or nitrogen, R3 being dropped if X is nitrogen comprising reacting azolium salts with a deprotonizing reagent in pure liquid ammonia or in pure organic amine or a mixture of liquid ammonia or an organic amine and an organic polar-aprotic solvent which are a plurality of temperature-sensitive carbenes are produced under mild reaction conditions at temperatures of between -75 and 0 DEG C.