Process for the in vitro proliferation of cells which have been terminally differentiated through infection with Adenovirus and expression of E1A protein

摘要

Process for the proliferation of terminally differentiated mammal and avian cells comprising the stages of: infecting the said cells with an Adenovirus capable of effectively expressing the mRNA 12 S coded for by the Adenovirus E1A gene, incubating the infected cells in a growth medium comprising growth factors capable of inducing the proliferation of precursors of the said terminally differentiated cells, or serum. IMAGE