USE OF ACILCARNITINE ESTERS WITH ALIPHATIC LONG CHAIN ALCOHOLS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS WITH ANTIMICOTIC ACTIVITY.

摘要

THIS INVENTION REFERS TO THE ESTERS OF THE L-CARNITINES OF ACIL OF GENERAL FORMULA (I): WHERE R IS A RIGHT OR BRANCHED ACIL GROUP THAT HAS 2 TO 16 ATOMS OF CARBON, IN PARTICULAR ISOBUTIRILE AND ISOVALERYL; N IS AN INTEGER UNDERSTANDING BETWEEN 7 AND 15, PARTICULARLY 10; AND X IS THE ANION OF A PHARMACOLOGICALLY ACCEPTED ACID THEY ARE EQUIPPED WITH A POWERFUL ANTIMYCHOTIC ACTIVITY ESPECIALLY AGAINST YEAST-TYPE FUNGI, SUCH AS CANDIDA ALBICANS, THE ETIOLOGICAL AGENT OF CANDIDIASIS, ASIGUS ASIGILLS, ASIGOS ASIGILLES PHARMACEUTICAL COMPOSITIONS BY ORAL OR PARENTERALLY ADMINISTRABLE OR TOPICALLY APPLICABLE CONTAIN AN ESTER OF FORMULA (I) AS AN ACTIVE INGREDIENT.