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ERYTHRO-HYDROXYNONYLADENINE ANALOGS WITH ENHANCED LIPOPHILIC AND ANTI-ISCHEMIA TRAITS
ERYTHRO-HYDROXYNONYLADENINE ANALOGS WITH ENHANCED LIPOPHILIC AND ANTI-ISCHEMIA TRAITS
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机译:脂多糖和抗缺血性状的红-羟基壬二烯类似物
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摘要
Analogs of erythro-hydroxynonyladenine (EHNA) are disclosed which have beenmodified by bonding various types of moieties tothe #8 or #9 carbon atoms in the "side chain" portion of the molecule. Thecompounds inhibit the intracellular enzymatic activity ofadenosine deaminase and are therapeutically effective in reducing hypoxic andischemic damage in heart and brain tissue.
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