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Fluorochemical solutions for the delivery of lipophilic phar maceutical agents

机译:用于输送亲脂性​​药物的氟化学溶液

摘要

A thermodynamically stable molecular solution providing enhanced bioavailability for lipophilic pharmaceutical agents, comprising a liquid carrier comprising one or more physiologically acceptable lipophilic fluorochemicals, and a pharmaceutically effective amount of at least one lipophilic pharmaceutical agent in said liquid carrier to form a thermodynamically stable molecular solution, optionally also including a co-solvent for facilitating solubilization of the pharmaceutical agent. Methods of making and using the molecular solution are also disclosed.
机译:一种热力学稳定的分子溶液,为亲脂性药物提供了更高的生物利用度,包括一种液体载体,该液体载体包含一种或多种生理上可接受的亲脂性含氟化合物,以及在所述液体载体中药学有效量的至少一种亲脂性药物,以形成热力学稳定的分子溶液,任选地还包括助溶剂的增溶助溶剂。还公开了制备和使用分子溶液的方法。

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