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Translocation signal facilitated nuclear delivery of macromolecules
Translocation signal facilitated nuclear delivery of macromolecules
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机译:易位信号促进大分子的核传递
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摘要
Methods for introducing proteins or nucleotide sequences into the nucleus using a novel receptor-mediated delivery system. The delivery system construct includes a cell receptor-binding domain, a cytoplasmic translocation domain, and a nuclear translocation signal domain. This system can transport functional macromolecule that will act once internalized into the nucleus.
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