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Removal of selected factors from whole blood or its components and prevention and treatment of septic shock syndrome
Removal of selected factors from whole blood or its components and prevention and treatment of septic shock syndrome
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机译:从全血或其成分中去除某些因素,并预防和治疗败血性休克综合症
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摘要
This invention provides a composition, device and method for the removal of selected factors, such as cytokines or pharmaceuticals, from a substance such as whole blood or plasma. Advantageously, the invention provides for the treatment or prevention of septic shock syndrome or other conditions evidenced by the presence of cytokines in a patient by contacting the patient's whole blood with a composition comprising silica and a surface treatment material, such as heparin, but preferably human serum albumin (HSA). The treatment lowers the cytokine concentration of the blood. Pharmaceuticals can be removed from an individual's whole blood or plasma, such as for use in treating drug overdosage.
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