NOVEL 5-HYDROXYPYRROLIDONE-2 DERIVATIVES ISOLATED FROM CERTAIN STRAINS OF PENICILLIUM AND SCLEROPHOMA AND THEIR USE AS PAF SYNTHESIS MODULATORS

摘要

Compounds of Formula (I) and (II) that selectively modulate the remodeling pathway of platelet activating factor (PAF) are described. Related pharmaceutical compositions and methods are also disclosed. These compounds, pharmaceutical compositions and methods are useful for reducing or eliminating inflammation.