METHOD FOR MEASURING PHYSICOCHEMICAL PROPERTIES OF TISSUES OR CELLS, METHOD FOR EXAMINING CHEMICALS, AND APPARATUS THEREFOR

摘要

A method for measuring the physicochemical properties of tissues or cells for arbitrarily varying the physicochemical environment around the tissues or cells depending on the purpose of an experiment and an apparatus therefor. The apparatus involves means (40) for maintaining the regular physicochemical environment around a tissue or cells of an organism; means (50) for arbitrarily varying the physicochemical environment; means (10 and 20) for measuring the physicochemical properties of the above-mentioned tissue or cells; and means (30) for comparing the physicochemical properties of the tissue or cells before and after varying the physicochemical environment. The monitoring means (10) is a potentiometer for measuring the electrical and physiological properties of the tissue or cells which involves an integrated cell installation system (1) provided with two or more micro-electrodes (11) on a substrate, cell installation members (6) located thereon for installing the above-mentioned tissue or cells and a leading pattern (12) whereby electric signals are supplied to the micro-electrodes (11) and drawn out therefrom.