This invention provides new antifungal compounds of Formula I or II: or Formula II: whereinn is 3 to 10;R is hydrogen, C1-C4 alkyl or a pharmaceutically acceptable salt cation selected from the group consisting of sodium, potassium, calcium, lithium, magnesium, ammonium, and tetra(C1-C4)alkyl ammonium; and R1 is hydrogen or methyl and in formula I, R2 is hydrogen or methyl: and their production by fermentation and use as antifungal agents.
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机译:本发明提供了式I或II的新的抗真菌化合物: <图像文件=“ IMGA0001.GIF” he =“ 68” id =“ ia01” imgContent =“ chem” imgFormat =“ GIF” wi =“ 92” /> Chemistry> 或公式II: <图像文件=“ IMGA0002.GIF” he =“ 66” id =“ ia02” imgContent =“ chem” imgFormat =“ GIF” wi =“ 85” /> Chemistry> 其中n为3至10;R是氢,C 1 Sub> -C 4 Sub>烷基或选自钠,钾,钙,锂,镁,铵和四的药学上可接受的盐阳离子(C 1 Sub> -C 4 Sub>)烷基铵;和R 1 Sup>是氢或甲基,在式I中,R 2 Sup>是氢或甲基:及其通过发酵生产并用作抗真菌剂。
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